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- n. Any of a family of heparan sulfate proteoglycans, anchored to the cell surface via a covalent linkage to glycosylphosphatidylinositol.
Sorry, no etymologies found.
Campos-Xavier AB, Martinet D, Bateman J, Belluoccio D, Rowley L, et al. (2009) Mutations in the heparan-sulfate proteoglycan glypican 6 (GPC6) impair endochondral ossification and cause recessive omodysplasia.
Hughes-Benzie RM, MacKenzie A, Baybayan P, Chen EY, et al. (1996) Mutations in GPC3, a glypican gene, cause the Simpson-Golabi-Behmel overgrowth syndrome.
The GPC5 gene encodes glypican 5, a member of the heparan sulfate preoteoglycans (HSPGs) that are bound to the external surface of the plasma membrane by glycosyl-phosphatidylinositol (GPI) linkage
Veugelers M, Vermeesch J, Watanabe K, Yamaguchi Y, Marynen P, et al. (1998) GPC4, the gene for human K-glypican, flanks GPC3 on xq26: deletion of the GPC3-GPC4 gene cluster in one family with Simpson-Golabi-Behmel syndrome.
There are six glypican family members in the Human Genome (GPC1 to GPC6).
The GPC5 gene encodes glypican 5, one of the six members of the heparan sulfate proteoglycan (HSPG) family.
GPC3 is a member of the glypican family of glycosylphosphatidylinositol-anchored cell-surface heparan sulfate proteoglycans.