Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. Plural form of granzyme.

Etymologies

Sorry, no etymologies found.

Examples

  • However, these attackers also require tactics: in order to destroy a target cell, the attackers need to smuggle their weapons, known as granzymes, into the afflicted cell.

    Scientific Blogging

  • By binding to CD3 co-receptor on the T cell, the antibody activates the immune system T cell and instigates the delivery of the T cell cytolytic proteins, perforins and granzymes, into the cancer cells.

  • Enzymes are injected that dissolve the mitochondria that power cell functions, and finally, granzymes are injected that chop up the DNA in the nucleus like a molecular Pac-Man.

    The Earth Times Online Newspaper

  • Our previous studies suggest that several effector mechanisms, such as perforin, granzymes, or complements, may be involved in the killing of cancer cells.

    BioMed Central - Latest articles

  • Despite more than twenty years of research, however, it remained unclear as to which of these pathways is used to smuggle the lethal amount of granzymes into a cell.

    Later On

  • "We were also able to show that the pores are large enough to allow enough granzymes into the cell before the holes are resealed."

    Later On

  • Scientists at the Max Planck Institute of Neurobiology have now shown that minute pores on the cell surface open the door to the granzymes for a short period of time.

    Later On

  • Contrary to the generally accepted view, the membrane holes now seem to be the main point of entry for granzymes.

    Later On

  • But the body puts up a fight: specialized cells in the immune system smuggle small molecules (granzymes) into cancer cells and those body cells that have fallen prey to viruses.

    Later On

  • Perforin might thus provide the granzymes with the openings they require.

    Later On

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