from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. An enzyme that supercoils DNA.


Sorry, no etymologies found.


  • One of my favorites is a protein called gyrase, which can literally tie DNA into knots.

    The Edge of Evolution

  •  The most important change was in an enzyme called DNA gyrase that helps the bacteria replicate their DNA.

    Drug Resistance

  • In terms of our big, everyday world, gyrase is somewhat like a machine that could tie shoelaces.

    The Edge of Evolution

  • In particular, preliminary data show potent target inhibition of the Mycobacterium tuberculosis gyrase enzyme which translated in vitro to good antibacterial activity against drug-resistant tuberculosis. News Articles

  • The new compounds in the series to be studied demonstrate excellent inhibition of the essential bacterial enzyme DNA gyrase, and have improved metabolic stability. News Articles

  • Mycobacterium xenopi DNA gyrase A (Mxe GyrA) intein using protein semisynthesis.

    Naturejobs - All Jobs

  • They said antibiotic molecule, simocyclinone D8 (SD8), slots into pockets in the surface of a bacterial enzyme, DNA gyrase, and inhibits its activity.

    Gaea Times (by Simple Thoughts) Breaking News and incisive views 24/7

  • "The discovery of reverse gyrase in Nautilia profundicola suggests that it plays a key role in this microbe's ability to thrive near deep-sea hydrothermal vents, where conditions are thought to resemble those found on early Earth," said Matt Kane, program director in the National Science Foundation (NSF) 's Division of Environmental Biology, which funded the research.

    NSF News

  • One gene, called rgy, allows the bacterium to manufacture a protein called reverse gyrase when it encounters extremely hot fluids from the Earth's interior released from the sea floor.

    NSF News

  • (DSBs) by trapping DNA gyrase and topoisomerase IV on DNA.

    BioMed Central - Latest articles


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