Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun organic chemistry A
coccidiostat used inveterinary medicine ; asynthetic halogenated derivative offebrifugine .
Etymologies
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Examples
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Mice with a multiple sclerosis-like disease were far less severely affected when given low doses of the hydrangea-based drug, which is called halofuginone, the journal Science reported.
Latest Articles 2009
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Science, they show that a small-molecule compound known as halofuginone inhibits the development of Th17 cells, immune cells recently recognized as important players in autoimmune disease, without altering other kinds of T cells involved in normal immune function.
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Science, they show that a small-molecule compound known as halofuginone inhibits the development of Th17 cells, immune cells recently recognized as important players in autoimmune disease, without altering other kinds of T cells involved in normal immune function.
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Ms. Furlong, president of Parent Project Muscular Dystrophy, says the patient-advocacy group might be interested in financially supporting Halo's efforts with halofuginone.
Families of Ill Children Try Drug Development Amy Dockser Marcus 2011
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Medica Venture Partners, an Israel-based venture capital company that set up Collgard to develop halofuginone, raised $20 million from investors to work on the drug, says Yoav Waizer , Medica's chief financial officer.
Families of Ill Children Try Drug Development Amy Dockser Marcus 2011
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The Wicka and Seckler families hired Marc Blaustein , a former executive at biotechnology company Dyax Corp., to oversee the halofuginone program through a new company they named Halo Therapeutics.
Families of Ill Children Try Drug Development Amy Dockser Marcus 2011
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Medica was surprised by the offer from the families to buy halofuginone, says Eli Hazum , the company's general partner.
Families of Ill Children Try Drug Development Amy Dockser Marcus 2011
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And Collgard, which was exploring halofuginone for other diseases, had run trials in people that provided safety data on the drug.
Families of Ill Children Try Drug Development Amy Dockser Marcus 2011
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They injected mice for three to six days with halofuginone, which mimics the effects of being deprived of tryptophan, and found that it protected the kidneys as well.
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(In mice with another form of EAE that doesn't involve Th17 cells, halofuginone had no effect.)
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