haploidentical love

Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • adjective genetics Having the same haplotype

Etymologies

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Examples

  • When a patient and donor are mismatched (known as haploidentical transplants), high doses of stem cells can overcome rejection, a principle that has been successfully pioneered in animal models by study co-author Yair Reisner, MD.

    EurekAlert! - Breaking News 2009

  • When a patient and donor are mismatched (known as haploidentical transplants), high doses of stem cells can overcome rejection, a principle that has been successfully pioneered in animal models by study co-author Yair Reisner, MD.

    EurekAlert! - Breaking News 2009

  • When a patient and donor are mismatched (known as haploidentical transplants), high doses of stem cells can overcome rejection, a principle that has been successfully pioneered in animal models by study co-author Yair Reisner, MD.

    unknown title 2009

  • Esser R, Zimmermann S, Tonn T, Kotchetkov R, et al. (2005) Ex vivo expansion of highly purified NK cells for immunotherapy after haploidentical stem cell transplantation in children.

    PLoS ONE Alerts: New Articles Jan Spanholtz et al. 2010

  • In addition, haploidentical NK cell infusions together with IL-2 in a non-transplantation setting have been associated with complete hematologic remission in poor-prognosis patients with AML

    PLoS ONE Alerts: New Articles Jan Spanholtz et al. 2010

  • Ruggeri et al. demonstrated that NK cell alloreactivity can control relapse of acute myeloid leukemia (AML) without causing graft-versus-host disease (GVHD) in the setting of HLA-mismatched haploidentical allogeneic SCT

    PLoS ONE Alerts: New Articles Jan Spanholtz et al. 2010

  • Meyer-Monard S, Passweg J, Siegler U, Kalberer C, Koehl U, et al. (2009) Clinical-grade purification of natural killer cells in haploidentical hematopoietic stem cell transplantation.

    PLoS ONE Alerts: New Articles Jan Spanholtz et al. 2010

  • Ruggeri et al. demonstrated that NK cell alloreactivity can control relapse of acute myeloid leukemia (AML) without causing graft-versus-host disease (GVHD) in the setting of HLA-mismatched haploidentical allogeneic SCT

    PLoS ONE Alerts: New Articles Jan Spanholtz et al. 2010

  • These ex vivo-generated NK cell products can be exploited for adoptive immunotherapy either following haploidentical SCT for boosting NK cell-mediated graft-versus-leukemia reactivity or in the non-transplant setting following lymphodepleting immunosuppressive regimens.

    PLoS ONE Alerts: New Articles Jan Spanholtz et al. 2010

  • Soignier Y, Panoskaltsis-Mortari A, McNearney SA, Yun GH, et al. (2005) Successful adoptive transfer and in vivo expansion of human haploidentical NK cells in patients with cancer.

    PLoS ONE Alerts: New Articles Jan Spanholtz et al. 2010

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