Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. Plural form of helicase.

Etymologies

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Examples

  • (Oct. 28, 2005) - Researchers studying how proteins called helicases travel along strands of DNA have found that when the proteins hit an obstacle they snap back to where they began, repeating the process over and ... > read more

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  • The two molecular biologists initially discovered that this motor protein burns energy in the same way as enzymes called helicases and, like helicases, attached to the dividing sections of DNA.

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  • Via Dara Sosulski, highlighting a sentence from a scientific paper she was reading, “The ping-pong cycle acts independently of Piwi and Armitage but requires the function of Aubergine, the RNA helicases Spindle-E and Vasa, and the Tudor-domain protein Krimper.”

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  • Why would single-stranded binding proteins and DNA topoisomerases evolve prior to DNA helicases?

    Dawkins Tries to Find God

  • The structure of yeast Prp43p-ADP reveals the homology of DEAH helicases to DNA helicases and the presence of an oligonucleotide-binding motif.

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  • The structure of Prp43p provides the framework for functional and genetic analysis of all DEAH helicases. helicase,

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  • DEAH helicases participate in pre-messenger RNA splicing and ribosome biogenesis.

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  • Transcription factor II (TFIIH) that incorporate two helicases: XPB and XPD that unwinds a 30 bp DNA fragment around the DNA damage.

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  • DEXD / H-box RNA helicases couple ATP hydrolysis to RNA remodeling by an unknown mechanism.

    Journal of Biological Chemistry current issue

  • Promotion of UvrD-catalyzed unwinding of nicked duplexes by UvrAB may also explain the need for UvrAB and UvrD in Okazaki fragment processing in cells lacking DNA polymerase I. More generally, these data support the idea that helicase activity is regulated in vivo, with helicases acting as part of multisubunit complexes rather than in isolation.

    Journal of Biological Chemistry current issue

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