from Wiktionary, Creative Commons Attribution/Share-Alike License
- adj. Common misspelling of hematopoietic.
Sorry, no etymologies found.
Syk, or spleen tyrosine kinase, is an enzyme implicated in several hematopoeitic malignancies, like leukemia, that are a result of unregulated proliferation of stem cells.
Since the effects of WBI of 10.4 Gy are secondary to combined hematopoeitic and gastrointestinal syndrome, we wanted to induce primarily a radiation-induced gastro-intestinal injury in mice.
Gy WBI can induce both hematopoeitic and gastrointestinal injury, we also administered escalating doses (12-16 Gy) of whole abdominal irradiation (AIR) after shielding the thorax, head and neck and extremities and protecting a significant portion of the bone marrow, thus inducing predominantly RIGS.
In our experiments, Rspo1 could not prevent the mortality of the animals from the hematopoeitic syndrome, since all animals receiving WBI + AdRSpo1 were dead by 25-28 days.