from The American Heritage® Dictionary of the English Language, 4th Edition

  • adj. Embryology Exhibiting cleavage in which the entire egg separates into individual blastomeres.

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • adj. Cleaving, and separating into separate blastomeres.

from the GNU version of the Collaborative International Dictionary of English

  • adj. Undergoing complete segmentation; composed entirely of germinal matter, the whole of the yolk undergoing fission; -- opposed to meroblastic.

from The Century Dictionary and Cyclopedia

  • Wholly germinal: applied by Remak to those eggs in which the whole yolk is formative—that is, undergoes segmentation in development: opposed to meroblastic. Mammals, excepting monotremes, have holoblastic eggs. See cut under gastrulation.


from Wiktionary, Creative Commons Attribution/Share-Alike License

holoblast +‎ -ic


  • In the mammalian ova the nutritive yolk or deutoplasm is small in amount and uniformly distributed throughout the cytoplasm; such ova undergo complete division during the process of segmentation, and are therefore termed holoblastic.

    I. Embryology. 5. Segmentation of the Fertilized Ovum

  • WHOLE cell; hence Remak called it TOTAL segmentation, and the ova in question holoblastic, or "whole-cleaving."

    The Evolution of Man — Volume 1

  • Although the mass of the food-yelk may be very large in the ova of the discoblastic vertebrates, nevertheless in every case a blastula is developed from the morula, as in the holoblastic ova.

    The Evolution of Man — Volume 1

  • The multiplicity or loss of the vitellogenin (vtg) gene family in vertebrates has been argued to have broad implications for the mode of reproduction (placental or non-placental), cleavage pattern (meroblastic or holoblastic) and character of the egg (pelagic or benthic).

    BioMed Central - Latest articles


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