from The American Heritage® Dictionary of the English Language, 4th Edition

  • n. An active, complex enzyme consisting of an apoenzyme and a coenzyme.

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. A haloenzyme.


Sorry, no etymologies found.


  • The tRNA is combined with a particular amino acid; the holoenzyme catalyzes the transfer of the amino acid to the amino acid string attached to another part of the holoenzyme.

    Attached to Strings

  • The RNA, suitably edited, leaves the nucleus to combine with a ribosome and a tRNA, to form yet another holoenzyme.

    Attached to Strings

  • The overall shape of a sequence of the molecules in a particular stretch of DNA is such that it combines with a molecule (or collection of molecules) that we designate "RNA polymerase", to form a holoenzyme that catalyzes the addition of a particular ribonucleotide to a string of nucleotides, which we call "RNA".

    Attached to Strings

  • It is interesting to stress that the lower physical chemical stability of hybrid holoenzyme complexes does not raises functionality problems.

    A Top-down Approach

  • E, et al. (1996) RNA polymerase II holoenzyme contains SWI/SNF regulators involved in chromatin remodeling.

    PLoS Biology: New Articles

  • Fellows J, Li Y, de Bizemont T, Dirac AMG, et al. (1999) Elongator, a multisubunit component of a novel RNA polymerase II holoenzyme for transcriptional elongation.

    PLoS ONE Alerts: New Articles

  • Beckett D (2000) Function of a conserved sequence motif in biotin holoenzyme synthetases.

    PLoS ONE Alerts: New Articles

  • C-P4H subunits, the method detects the entire holoenzyme, and the signal is not disturbed by background expression of the separate subunits.

    BioMed Central - Latest articles

  • Then the following holoenzyme detection is accomplished by a goat anti-rabbit IgG labeled with alkaline phosphatase which AP catalyzes the reaction of a substrate transformation with fluorescent signal generation.

    BioMed Central - Latest articles

  • DNA polymerase is considered to be a holoenzyme since it requires a magnesium ion as a co-factor to function properly.

    Signs of the Times


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