Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. Plural form of homolog.

Etymologies

Sorry, no etymologies found.

Examples

  • Genes in the universal ancestor that were already homologs of each other (the paralogs such as elongation factors EF-1and EF-G used to root the universal tree, for instance [37]) of course complicate this view.

    A Disclaimer for Behe?

  • Do the various parts of the machine have homologs that are in turn part of a system that is more ancient than the machine?

    Behe and Gene discuss the Evolution of the Flagellum

  • Ongoing studies involve cell-cycle regulation, novel transcription factors and regulation of key genes involved in T cell anergy and tolerance, including Foxp3 and its various homologs; further details are available.

    Basic Biliary Atresia Research

  • Highly conserved protein interaction motifs and co-expression in sponges of multiple proteins whose homologs interact in eumetazoan synapses indicate that a complex protein scaffold was present at the origin of animals, perhaps predating nervous systems.

    Another predictable argument against front-loading

  • Of the 6,968 protein families that have so-called homologs – proteins that have similar amino acid sequences, often reflecting a similar or related function among the species — they found that Chlamy shared 35% (2,489/6,968) with both flowering plants and humans, and an additional 10% (706/6,968) with humans but not with flowering plants.

    Chlamy Has Something to Say

  • They draw on Hartman's and Federov's work on eukaryotic signature proteins (ESPs) – that is, proteins that are widespread in eukaryotes but with no homologs in prokaryotes.

    Amoeba supports front-loading

  • Total number "unique" (no known homologs): 15 (36%)

    Congratulations are in Order

  • Thus the present scenario predicts that careful multiple alignment of FliH sequences with bacterial F0-b and the corresponding archaeal and eukaryotic homologs (all of which would be equally related to FliH) will confirm homology.

    Congratulations are in Order

  • Sure, you identified the bulk of homologs for the Flagellum but you failed for two critical proteins.

    Congratulations are in Order

  • Jackson and Plano (2000) report that the Yersinia pestis FliH homolog YscL (corresponding to SctL/HrpE in Figure 4a) has low but significant sequence similarity with the e subunit of the archaeal ATPase of Methanococcus jannaschii and the e subunit of the vacuolar ATPase of Desulfurococcus spp.; these subunits are the homologs of the b subunit of the F1F0-ATP synthetase.

    Congratulations are in Order

Comments

Log in or sign up to get involved in the conversation. It's quick and easy.