Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun Plural form of
homolog .
Etymologies
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Examples
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Ongoing studies involve cell-cycle regulation, novel transcription factors and regulation of key genes involved in T cell anergy and tolerance, including Foxp3 and its various homologs; further details are available.
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Do the various parts of the machine have homologs that are in turn part of a system that is more ancient than the machine?
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Ongoing studies involve cell-cycle regulation, novel transcription factors and regulation of key genes involved in T cell anergy and tolerance, including Foxp3 and its various homologs; further details are available.
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Genes in the universal ancestor that were already homologs of each other (the paralogs such as elongation factors EF-1and EF-G used to root the universal tree, for instance [37]) of course complicate this view.
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Highly conserved protein interaction motifs and co-expression in sponges of multiple proteins whose homologs interact in eumetazoan synapses indicate that a complex protein scaffold was present at the origin of animals, perhaps predating nervous systems.
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Of the 6,968 protein families that have so-called homologs – proteins that have similar amino acid sequences, often reflecting a similar or related function among the species — they found that Chlamy shared 35% (2,489/6,968) with both flowering plants and humans, and an additional 10% (706/6,968) with humans but not with flowering plants.
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They draw on Hartman's and Federov's work on eukaryotic signature proteins (ESPs) – that is, proteins that are widespread in eukaryotes but with no homologs in prokaryotes.
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Total number "unique" (no known homologs): 15 (36%)
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Thus the present scenario predicts that careful multiple alignment of FliH sequences with bacterial F0-b and the corresponding archaeal and eukaryotic homologs (all of which would be equally related to FliH) will confirm homology.
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Sure, you identified the bulk of homologs for the Flagellum but you failed for two critical proteins.
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