Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. Plural form of hydroxylase.

Etymologies

Sorry, no etymologies found.

Examples

  • It is the chemical that gets into the body via smoke but then is converted by enzymes called aryl hydrocarbon hydroxylases into a more potent chemical that is the epoxide of BP.

    The New Super-Nutrition

  • HIF-1 activity depends on the inhibition of the post-transcriptional hydroxylation of the subunit α by prolyl hydroxylases

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  • PC, Oh J, Kelly B, Krishnamachary B, et al. (2005) OS-9 interacts with hypoxia-inducible factor 1alpha and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1alpha.

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  • During hypoxia, however, inactivation of the prolyl-hydroxylases occurs, resulting in the stabilisation of HIF-α on account proteasomal degradation of the subunit being inhibited.

    Conservapedia - Recent changes [en]

  • In mammals, three types of HIF prolyl-hydroxylases that have been identified: PHD1 (prolyl-hydroxylase domain), PHD2 and PHD3.

    Conservapedia - Recent changes [en]

  • In mammals, three types of HIF prolyl-hydroxylases that have been identified: PHD1

    Conservapedia - Recent changes [en]

  • Deletion of the ODDD in the HIF-1α / Fluc fusion protein prevents hydroxylation by prolyl-hydroxylases and abrogates HIF-1α (ODDD) - pVHL interaction.

    PLoS ONE Alerts: New Articles

  • HIF-1α protein is constantly modified posttranslationally by prolyl hydroxylases at Pro402 and / or Pro564 within the oxygen-dependent degradation (ODD) domain which promotes binding with pVHL (von Hippel-Lindau protein) and subsequent targeting for rapid proteasomal degradation.

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  • In addition, our reporter systems demonstrated that various cell lines responded differently to inhibition of a prolyl hydroxylases, either by hypoxia or CoCl

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  • T. gondii aromatic amino acid hydroxylases expressed in this study.

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