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- noun biochemistry The excessive
acetylationof the lysineresidues of a protein(especially of a histone)
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Domain-wide hyperacetylation was strongly reduced by treatment with actinomycinD but not with the protein synthesis inhibitor cycloheximide (CHX).
(C) Transcription is required for inducible H3K9 hyperacetylation at the transcribed region upstream of Cxcl11.
P21WAF1 / cip1 promoters by Smad1 / 5 / 8 to induce the hyperacetylation of histones H3 and