Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun uncountable Frequent mutation
  • noun countable The organism or gene that results from such a mutation

Etymologies

Sorry, no etymologies found.

Examples

  • The same thing goes for the immune system (progressive improvement of binding), but somatic hypermutation is an informationally-driven process, with selection (and, in the case of SMH, it is an artificial selection) accounting for only a small part of the innovation.

    A New Book

  • When such patients were treated with Temodar and subsequently had a recurrence of the tumor, it was very likely to become resistant to treatment because of "hypermutation" -- an increased rate of gene changes that led to the tumor's ability to evade the drugs.

    The Medical Quack

  • When such patients were treated with Temodar and subsequently had a recurrence of the tumor, it was very likely to become resistant to treatment because of "hypermutation" -- an increased rate of gene changes that led to the tumor's ability to evade the drugs.

    The Medical Quack

  • When such patients were treated with Temodar and subsequently had a recurrence of the tumor, it was very likely to become resistant to treatment because of "hypermutation" -- an increased rate of gene changes that led to the tumor's ability to evade the drugs.

    The Medical Quack

  • When such patients were treated with Temodar and subsequently had a recurrence of the tumor, it was very likely to become resistant to treatment because of "hypermutation" -- an increased rate of gene changes that led to the tumor's ability to evade the drugs.

    The Medical Quack

  • It is thus not inconceivable that some of the sequences in the proposed Universal Genome in the Origin of Metazoa might have no immediate effect on fitness, but still have a function by acting as a reservoir of genetic material on which variation inducing mechanisms such as sequence duplication, somatic hypermutation, gene conversion and homologous recombination can act upon during periods of selection.

    2008 September - Telic Thoughts

  • It might tell us what its direct evolutionary history is, maybe allow us to distinguish genetic 'borrowings' [HGT] from duplication-hypermutation from top-down organization of trans-retrotrans pieces-parts.

    Darwin's Defenders Go Neo-Lamarckian

  • Our favorite heroes in many comic series are just ordinary Janes and Joes, thrust into extraordinary circumstances by fate, radioactive ooze or genetic hypermutation.

    Jonah Lalas: Obama At Comic Con

  • The research findings still generate a lot of ink, but so far no researcher has empirically established via pre or post-selection genome sequencing of individual cells in the experimental population that triggered hypermutation occurs in ALL genes.

    Analogy, How Scientifically Powerful is It?

  • Further extension of this class through iterative somatic hypermutation yielded fluorescent proteins with emission wavelengths up to 650 nanometers.

    Archive 2005-10-01

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