Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun Either of the peptide hormones orexin

Etymologies

from The American Heritage® Dictionary of the English Language, 4th Edition

[hypo(thalamus) + (in)cretin.]

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Examples

  • The gene turned out to be a receptor for a neurotransmitter called hypocretin or orexin (it has two different names because it was discovered at two different research labs the same year and named independently by both).

    In Search Of Sleep 2008

  • What we know so far is that a previously unknown neurotransmitter a chemical that nerve cells release to stimulate other nerve cells called hypocretin or orexin has been found in the lateral hypothalamus, a region of the brain known to be important in the control of certain basic body functions such as appetite.

    Solve Your Child’s Sleep Problems M.D. Richard Ferber 2006

  • What we know so far is that a previously unknown neurotransmitter a chemical that nerve cells release to stimulate other nerve cells called hypocretin or orexin has been found in the lateral hypothalamus, a region of the brain known to be important in the control of certain basic body functions such as appetite.

    Solve Your Child’s Sleep Problems M.D. Richard Ferber 2006

  • There is also some evidence that a brain chemical called hypocretin plays a role in narcolepsy.

    Medlogs - Recent stories 2009

  • There is also some evidence that a brain chemical called hypocretin plays a role in narcolepsy.

    Health News from Medical News Today 2009

  • The mutant fish lacked a working receptor for hypocretin, a neuropeptide that is secreted in normal fish by neurons in the region of the brain that controls hunger, sex and other basic behaviours.

    Fish Suffer From Insomnia, Scientists Reported on Monday. | Impact Lab 2007

  • Lower glucose levels in the brain may also lead to a stronger stress-catecholamine response, changes in hypocretin, similar to being on stimulants.

    Last gasp of the dark ages of nutrition | The Blog of Michael R. Eades, M.D. 2009

  • That meshes with Saper's sleep-switch model: he proposes that hypocretin is the chemical in the hypothalamus most likely responsible for pushing the switch in the direction of wakefulness.

    In Search Of Sleep 2008

  • Several weeks after Mignot's team published its finding, another team at the University of Texas Southwestern Medical Center at Dallas published a study showing that if hypocretin is knocked out of mice, the result is also a condition that resembles narcolepsy.

    In Search Of Sleep 2008

  • The receptor has a mutation in narcoleptic dogs, leaving hypocretin with nothing to bind to.

    In Search Of Sleep 2008

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