from Wiktionary, Creative Commons Attribution/Share-Alike License

  • adj. Having fewer than the diploid number of chromosomes


from Wiktionary, Creative Commons Attribution/Share-Alike License

From hypo- +‎ diploid


  • Neutrophils from healthy volunteers were incubated with DFP (2.5 mM), and neutrophil elastase (NE) activity; hypodiploid DNA formation; caspases-3 and -8 processing and activity; exteriorization of phosphatidylserine (PS); oxidative burst activity and hydrogen peroxide release were measured.

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  • The earliest detectable evolutionary stage was a hypodiploid clone which, by clustering of the sequencing profiles of geographical "neighbor" segment sequences, appeared to have undergone five major steps of mutation, acquiring many additional focal amplifications and deletions of cancer genes including in one cases, - medical news plus CME for physicians

  • The numbers reported on the left and on the right of each histograms represents the mean percentage±SD of hypodiploid and of >

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  • Confirmation of apoptosis was made by hypodiploid PI staining and loss of mithochondrial membrane potential.

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  • Apoptotic cells are characterized by a lower DNA content (hypodiploid cells) because of nuclear fragmentation.

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  • Note the decreased number of hypodiploid apoptotic HPMC in TNFα/IFNγ/QM56 treated cells (black arrow).

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  • Cells treated with H35N (a mutant of α-HL that remains as membrane bound monomer), have been shown to accumulate hypodiploid nuclei, activate caspases and induce intrinsic mitochondrial apoptotic pathway.

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  • BCR-ABL1-positive ALL, hypodiploid ALL, and ALL in infants) were excluded from this cohort.

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  • A-C), and decreased apoptosis as assessed by the presence of hypodiploid cells (Fig. 2.

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