from Wiktionary, Creative Commons Attribution/Share-Alike License
- n. Decreased ability to move a joint of the body.
The results of this Phase 1 pilot study are consistent with the use of APl-130277 as an acute rescue treatment of hypomobility in advanced PD and illustrate the product's potential to replace apomorphine injections.
Apomorphine, a potent dopamine agonist, is currently the only drug approved specifically for the treatment of acute motor fluctuations/hypomobility freezing or "off" episodes in patients with advanced Parkinson's disease.
Exclusion criteria from the study were: previous anti-incontinence surgery, pelvic organ prolapse requiring treatment, any coexistent pelvic pathology, urethral hypomobility (