hypophosphorylated love



from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • adjective biochemistry phosphorylated to a less than normal extent, or less than fully


from Wiktionary, Creative Commons Attribution/Share-Alike License

From hypo- +‎ phosphorylated


  • This hypophosphorylated form of Rb is now capable of binding to E2F family members, resulting in suppression of their transcriptional transactivation potential during early G

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  • Concurrent with this timeframe, the Rb protein is hypophosphorylated and MCMs have not loaded onto chromatin at the preRCs.

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  • Moreover, the ZAK-RhoGDIbetainteraction may maintain ZAK in an inactive hypophosphorylated form.

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  • KaiC, a central clock protein in cyanobacteria, undergoes circadian oscillations between hypophosphorylated and hyperphosphorylated forms in vivo and in vitro.

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  • Accordingly, connection between the ubiquitin ligase MID1 / α4 and microtubule-associated PP2Ac is disrupted, the enzyme accumulates and microtubule-associated proteins are hypophosphorylated

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  • Overexpression of cyclin D1 and cdk4 also affects later events in the FGF response The maintenance of FGF-induced growth arrest is characterized by the accumulation of hypophosphorylated p130 by 10-16 hrs of FGF treatment, that follows a dramatic drop in cyclin E / cdk2 activity between 6 and 12 hrs

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