Definitions
from The Century Dictionary.
- Of or related to a particular class or type. See
idiotype .
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- adjective Of or pertaining to an
idiotype
Etymologies
from Wiktionary, Creative Commons Attribution/Share-Alike License
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Examples
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The lab's third project deals with the elucidation of the molecular basis of antigen mimicry by anti-idiotypic antibodies.
YubaNet.com 2009
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Claim 92 of the Alonso patent application claims a "method of treating neurofibrosarcoma in a human by administering an effective amount" of an idiotypic monoclonal antibody (mAb) secreted in a human-human cell hybridoma.
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Claim 92 of the Alonso patent application claims a "method of treating neurofibrosarcoma in a human by administering an effective amount" of an idiotypic monoclonal antibody (mAb) secreted in a human-human cell hybridoma.
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Furthermore, anti-idiotypic antibodies and immune complexes may develop with repeated infections and affect GIA levels.
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In addition, the "efficacy" of antitumor therapy (a fact seemingly more related to operability and enablement than written description) is expected to be related to "idiotypic change in the original tumor" according to a scientific journal article by Dr. Alonso himself.
Patent Docs 2008
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A method of treating neurofibrosarcoma in a human by administering an effective amount of a monoclonal antibody idiotypic to the neurofibrosarcoma of said human, wherein said monoclonal antibody is secreted from a human-human hybridoma derived from the neurofibrosarcoma cells.
Patent Docs 2008
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As I understand it, Alonso's method requires production of a specific mAb for each patient (a monoclonal antibody idiotypic to the neurofibrosarcoma of "said" human).
Patent Docs 2008
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What Dr. Alonzo found was that for this particular type of cancer, neurofibrosarcoma, cells could be taken and used to make human idiotypic antibodies from the patient's own tumor, which could then be used to treat the patient with (admittedly) striking results.
Patent Docs 2008
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Now, a claim to a pharmaceutical composition comprising an idiotypic monoclonal antibody immmunologically reactive with a neurofibrosarcoma is the kind of "reach through" claim you seem to find objectionable, and there you are probably right on these facts.
Patent Docs 2008
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"old" method (here, mAb production) with a "new" result (here, unique idiotypic mAbs effective against a patient's cancer).
Patent Docs 2008
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