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immunosenescence

Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. The gradual deterioration of the immune system caused by the ageing process.

Etymologies

from Wiktionary, Creative Commons Attribution/Share-Alike License

immuno- +‎ senescence

Examples

  • The overall decline in immune function is called immunosenescence.

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  • As if equine Cushing's, metabolic syndrome, laminitis, and insulin resistance weren't enough to worry about in our aging horses, we can now add "immunosenescence" and

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  • Santoro A, Bellavista E, Bonafe M, Monti D, et al. (2003) Immunoproteasomes and immunosenescence.

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  • One of the strengths of our study is the low CMV-positivity rate (54%) in a relatively older population, which allows us to separate the effects of age and CMV status on immunosenescence.

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  • Future studies should focus on defining the potential role of the CMV-specific inflammatory response in non-AIDS morbidity and mortality, including immunosenescence.

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  • Why are immunosenescence and inflammaging important?

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  • A better understanding of immunosenescence and machanisms responsible for proven deleterious changes is needed to maintain a healthy state in later life and to design possible therapeutic interventions.

    BioMed Central - Latest articles

  • The chronological age at which immunosenescence becomes clinically important is known to be influenced by many factors, including the pathogen load to which individuals are exposed throughout life.

    BioMed Central - Latest articles

  • It is proposed here that the cancer antigen load may have a similar effect on "immune exhaustion" and that pathogen load and tumor load may act additively to accelerate immunosenescence.

    BioMed Central - Latest articles

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