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Examples
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In a search for mutants that got drunk unusually fast Heberlein built the inebriometer.
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More mutants originally known for their defects in memory and learning – rutabaga and fasciclin II – went throught the inebriometer and dropped out almost as fast as cheapdate.
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The first fly to drop out of Heberlein’s inebriometer, the appropriately-named cheapdate mutant, barely needed the fly equivalent of a Kahlua shot before it folded it up its wings and dropped.
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A – the alcohol without liquid (AWOL) inhaler; B – Dr. Heberlein’s inebriometer*.
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More mutants have been identified but haven’t yet been characterized to the same degree as cheapdate: lightweight has the same effect as cheapdate but acts on a different gene, while barfly and tipsy have opposite effects in the inebriometer, the former making flies more resistant to alcohol and the latter making them sensitive.
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