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Examples
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Pressure on Sanofi increased after its Multaq heart treatment, cleared for sale in 2009, was linked to possible liver complications and a promising cancer drug, called iniparib, failed in a key clinical study this year.
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Meg McArthur, senior policy officer at the charity Breakthrough Breast Cancer, said: We welcome research into Parp inhibitors such as iniparib, a class of drugs pioneered at our research centre, as they could be beneficial for an aggressive type of breast cancer.
Telegraph.co.uk - Telegraph online, Daily Telegraph and Sunday Telegraph 2010
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Sanofi-Aventis declined 3.8% in Paris after the drug giant said a trial evaluating its breast cancer drug iniparib didn't slow the progression of the disease or aid in survival rates.
Europe Stocks Drop Barbara Kollmeyer 2011
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Sanofi-Aventis declined 3.8% after the drug giant said a trial evaluating its breast-cancer drug iniparib didn't slow the progression of the disease or aid in survival rates.
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The French pharmaceutical giant said BSI-201, or iniparib, a treatment for metastatic triple-negative breast cancer, hadn't meet the criteria for significance for survival and progression-free survival.
Sanofi Suffers Cancer-Drug Setback Mimosa Spencer 2011
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The failure of breast cancer treatment BSI-201, or iniparib, to meet a goal in a late-stage study last month underscored the challenge of finding new products, even when they're purchased at an advanced development stage.
Sanofi CEO Bets on Genzyme Mimosa Spencer 2011
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New England Journal of Medicine, the experimental drug iniparib not only shrank tumors and increased the time they took to progress, but also surprised researchers by prolonging survival in women with what's known as triple-negative breast cancer.
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New England Journal of Medicine, the experimental drug iniparib not only shrank tumors and increased the time they took to progress, but also surprised researchers by prolonging survival in women with what's known as triple-negative breast cancer.
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In this study, 123 patients with triple-negative breast cancer were randomized to receive a commonly used, well-tolerated chemotherapy regimen gemcitabine and carboplatin or to receive chemo plus iniparib.
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The most common grade 3/4 adverse events in the iniparib treatment arm were neutropenia, anemia, thrombocytopenia, leukopenia and fatigue/asthenia.
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