Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. Any of many heterodimeric transmembrane proteins that function as receptors in communication between cells.

Etymologies

Sorry, no etymologies found.

Examples

  • In addition, Merck is developing cilengitide, which is the first in a new class of investigational anti-cancer therapies called integrin inhibitors to reach Phase III of development; it is currently being investigated for the treatment of glioblastoma, SCCHN and NSCLC.

    TradingMarkets

  • In addition, Merck is developing cilengitide, which is the first in a new class of investigational anti-cancer therapies called integrin inhibitors to reach Phase III of development; it is currently being investigated for the treatment of glioblastoma,

    The Earth Times Online Newspaper

  • Through their study, they identified a molecule - called LXY1 - that binds with high specificity to a particular cell-surface protein called alpha-3 integrin, which is overexpressed on cancer cells.

    Health News from Medical News Today

  • Nature Medicine on 22 March, suggested that such effects might also occur for a class of drugs called integrin inhibitors.

    Latest Articles

  • More specifically, they found that release of growth factor by GPR30 required the activation of a latent adhesion receptor (known as integrin 51).

    Emaxhealth

  • Together, these molecules, called integrin and netrin, may be a valuable new target in the efforts to halt cancer's spread via metastasis.

    THE MEDICAL NEWS

  • On the other hand, the significance of a complex control of NFAT5 subcellular localization in isotonic conditions might be found outside hypertonic stress responses, since this factor can also regulate osmotic stress-unrelated processes, such as integrin-induced migration, cell differentiation and viral replication The sustained association of NFAT5 with chromatin through mitosis and interphase caused by deletion of its CTD was consistent with the high stability of NFAT5-DNA complexes described previously in vitro

    PLoS ONE Alerts: New Articles

  • Likewise, choanoflagellates have five immunoglobulin domains, though they have no immune system; collagen, integrin and cadherin domains, though they have no skeleton or matrix binding cells together; and proteins called tyrosine kinases that are a key part of signaling between cells, even though Monosiga is not known to communicate, or at least does not form colonies.

    An Animal Toolkit in a Single-Celled Organism

  • It can cross-link a number of connective proteins, for example integrin, which allows inflammatory and wound-repair cells to migrate more easily to damaged sites.

    Behe vs Sea Squirts - The Panda's Thumb

  • Previously the big guns that were hyped to get the blood sugar down were the glitazones now less so and I see invitations coming in for drugs that are attempting to favorably harness the integrin family.

    Stochastic and epistemic uncertainty and the ecological fallacy

Comments

Log in or sign up to get involved in the conversation. It's quick and easy.