Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • adj. Capable of being ionized

from The Century Dictionary and Cyclopedia

  • Capable of being ionized: used both of electrolytes and of gases.

Etymologies

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Examples

  • Starting with the ionizable cationic lipid 1,2-dilinoleyloxy-3-dimethylaminopropane (DLinDMA), a key lipid component of stable nucleic acid lipid particles (SNALP) as a benchmark, we used the proposed in vivo mechanism of action of ionizable cationic lipids to guide the design of DLinDMA-based lipids with superior delivery capacity.

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  • Consequently, biochemists are interested in the pK values of the ionizable groups in proteins and how these pK values depend on their environment.

    Journal of Biological Chemistry current issue

  • The ionizable groups of PG-1 were protonated or deprotonated assuming the pH for the unbound peptide and peptide in the membrane model to be equal to 7.0.

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  • Similar results with substitutions of 6 randomly chosen internal positions in ribonuclease H with Lys and Glu suggest that the ability of proteins to tolerate internal ionizable groups might be a property common to many proteins.

    Proceedings of the National Academy of Sciences current issue

  • Internal ionizable groups are quite rare in water-soluble globular proteins.

    Proceedings of the National Academy of Sciences current issue

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