from The American Heritage® Dictionary of the English Language, 4th Edition

  • n. Any of a group of organic compounds that facilitate the transport of ions across the cell membrane.

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. any substance that can transfer ions from a hydrophilic medium (such as water) to a hydrophobic medium, or across a biological membrane, normally by forming a complex with it; an ion carrier

from the GNU version of the Collaborative International Dictionary of English

  • n. A compound that enhances transport of ions across cellular membranes, by binding them and carrying them across. As a class ionophores tend to be lipophilic in nature; each compound is usually specific for one or a small number of ions.


Sorry, no etymologies found.


  • The eggs were divided into two batches, one of which was fertilized, the other treated with calcium ionophore, A23187.

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  • Bronner C, Landry Y The effect of cromoglycate and of natural flavonoids on histamine release from peritoneal rat mast cells induced by compound 48/80 and ionophore

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  • In contrast, a short preincubation (2 min) of cells with quercetin or luteolin decreased their inhibitory effect on the ionophore-induced release, whereas a longer preincubation increased the inhibition.

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  • Preincubation of cells with cromoglycate, dihydroquercetin and amentoflavone, a biflavonoid, decreased the potency of drugs to inhibit the ionophore-induced release; the optimal inhibitions were observed when drugs were added simultaneously with the ionophore A23187.

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  • In fact, studies in animals and early, short-term clinical trials of zinc-ionophore drugs including clioquinol and PBT2 in people with Alzheimer's disease have so far produced promising results.

    R&D Mag - News

  • Third, we found that the calcium ionophore ionomycin caused ER fission but that, even in this case, ER fission required NMDA receptor activation.

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  • Apart from glutamate, the calcium ionophore ionomycin was able to induce ER fission.

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  • As control, we used a depolarized sample treated with ionophore Valynomicin for further 15 min after JC-1 staining.

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  • When stimulated with progesterone or A23187 (a calcium ionophore), sperm from these animals had a defective acrosome reaction.

    PLoS ONE Alerts: New Articles

  • Acrosome reaction experiments indicate that the basic problem in sperm from hyh mice is a reduced capacity to undergo exocytosis upon stimulation with progesterone and even with a calcium ionophore.

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