Definitions

from The American Heritage® Dictionary of the English Language, 5th Edition.

  • noun A biological specimen or other element that is a duplicate of the holotype.
  • noun Any of the subclasses of immunoglobulins defined by the chemical and antigenic characteristics of their constant regions.

from The Century Dictionary.

  • noun In zoögeog., a form common to two or more countries: applied to representatives of the same genus or family occurring in different countries.

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun immunology A marker corresponding to an antigen found in all members of a subclass of a specific class of immunoglobulins

Etymologies

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Examples

  • We asked if the medical isotype shortage caused by the shutdown of the Chalk River nuclear reactor will have any impact on my treatment.

    Another meeting with the surgeon « knitnut.net 2009

  • The Smu tandem repeat region is critical for Ig isotype switching in the absence of Msh2.

    3 recent reports use evolution to study mechanisms of antibody diversification - The Panda's Thumb 2006

  • The cells were fixed and permeabilized with Cytofix/Cytoperm ™ buffer (BD BioScience) for 20 minutes at 4°C and incubated with allophycocyanin anti-IFN-γ or corresponding isotype controls (eBioscience) for 20 minutes on ice.

    PLoS ONE Alerts: New Articles Xiaoling Gao et al. 2010

  • However, the immunoglobulin isotype repertoire in teleost fish is more limited than in e.g. mouse and humans and consists of only IgM, IgD and a unique fish isotype termed IgT

    PLoS ONE Alerts: New Articles Hans-Christian Ingerslev et al. 2010

  • IgG2a isotype antibody is known to be more effective than other isotypes in clearing virus infection via multiple mechanisms including complement activation, stimulation of antibody-dependent cellular cytotoxicity and clearance of opsonized virus by macrophages

    PLoS ONE Alerts: New Articles Fu-Shi Quan et al. 2010

  • After washing with a staining buffer, cells were incubated with anti-mouse CD16/32 (Fc block, e-Bioscience) for 30 min on ice to block the FcR non-specific binding and subsequently stained for surface markers with PE-anti-CD4, FITC-anti-CD3ε, PerCy-anti-CD8 or isotype controls for

    PLoS ONE Alerts: New Articles Xiaoling Gao et al. 2010

  • The surface marker expression (solid lines) or matched Ab isotype control (shaded histogram) are shown respectively.

    PLoS ONE Alerts: New Articles Xiaoling Gao et al. 2010

  • The florescence-conjugated appropriate isotype controls antibodies were used as control.

    PLoS ONE Alerts: New Articles Xiaoling Gao et al. 2010

  • Apart from being the acronym of 'International System Of TYpographicPicture Education, isotype is also Greek for' the same sign '.

    Efímera 2010

  • Landis ED, Phillips RB (2005) Discovery of a unique Ig heavy-chain isotype (IgT) in rainbow trout: Implications for a distinctive B cell developmental pathway in teleost fish.

    PLoS ONE Alerts: New Articles Hans-Christian Ingerslev et al. 2010

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