Definitions
from The American Heritage® Dictionary of the English Language, 5th Edition.
- noun Either of two submicroscopic attachment points for chromosomal microtubules, present on each centromere during the process of cell division.
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun the protein structure in
eukaryotes which assembles on thecentromere and links the chromosome tomicrotubule polymers from themitotic spindle duringmitosis
from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
- noun a specialized condensed region of each chromosome that appears during mitosis where the chromatids are held together to form an X shape
Etymologies
from The American Heritage® Dictionary of the English Language, 4th Edition
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Examples
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We now believe that proteins in a structure called the kinetochore are among the most sensitive to degradation or mutation.
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These complexes become attached to some of the spindle microtubules, which are then termed kinetochore microtubules.
unknown title 2009
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This force increases the efficiency with which chromosomes make bipolar spindle attachments and regulates kinetochore activities necessary for chromosome oscillation, but is not essential for chromosome congression.
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Spindle fibers, composed of microtubules, have attached to the sister pairs of chromosomes at their point of attachment the kinetochore, or centromere.
THE HIDDEN FACE OF GOD GERALD L. SCHROEDER 2001
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Spindle fibers, composed of microtubules, have attached to the sister pairs of chromosomes at their point of attachment the kinetochore, or centromere.
THE HIDDEN FACE OF GOD GERALD L. SCHROEDER 2001
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During meiosis, fibres called microtubules attach themselves to the centre kinetochore of the chromosomes.
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Overlaid onto these signals that promote orchestrated cell division are checkpoints that ensure appropriate mitotic spindle formation, a lack of DNA damage, kinetochore attachment, and that each daughter cell has the appropriate complement of DNA.
Elites TV PLoS ONE 2010
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The kinetochore protein Mtw1 was epitope-tagged, allowing us to score the number of kinetochore foci in spread nuclei.
PLoS ONE Alerts: New Articles David Obeso et al. 2010
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The initial study of centromere coupling reported that in chromosome spreads exhibiting centromere coupling, Zip1 foci and kinetochore pairs occur in approximately equal numbers (about sixteen) and exhibit a high level of co-localization
PLoS ONE Alerts: New Articles David Obeso et al. 2010
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Overlaid onto these signals that promote orchestrated cell division are checkpoints that ensure appropriate mitotic spindle formation, a lack of DNA damage, kinetochore attachment, and that each daughter cell has the appropriate complement of DNA.
Elites TV PLoS ONE 2010
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