kinetochores

In the absence of the nuclear membrane, the mitotic spindle microtubules are now free to enter the nuclear region, and formation of specialized protein complexes called kinetochores begins on each centromere.

unknown title 2009

In the absence of the nuclear membrane, the mitotic spindle microtubules are now free to enter the nuclear region, and formation of specialized protein complexes called kinetochores begins on each centromere.

unknown title 2009

In the absence of the nuclear membrane, the mitotic spindle microtubules are now free to enter the nuclear region, and formation of specialized protein complexes called kinetochores begins on each centromere.

unknown title 2009

Meiotic cells (DDO45 and DDO46) were evaluated for the behavior of centromeres by indirect immunofluorescence observation of kinetochores (Mtw1-13XMYC), a pair of homologous centromeres

PLoS ONE Alerts: New Articles David Obeso et al. 2010

Meiotic cells (DDO45 and DDO46) were evaluated for the behavior of centromeres by indirect immunofluorescence observation of kinetochores (Mtw1-13XMYC), a pair of homologous centromeres

PLoS ONE Alerts: New Articles David Obeso et al. 2010

Although meiosis and mitosis share a lot of similarities, numerous differences exist between the spindles in these types of cells and some of these differences have been already identified: (i) centrosomes are present in somatic cells and absent in oocytes; (ii) kinetochores microtubules appear very late in MI

PLoS ONE Alerts: New Articles Vincent Gache et al. 2010

We deliberately refrained from merging the identified proteins into complexes specific for the kinetochores and the centrosome, since we found in our screen only a limited number of proteins related to these structures.

PLoS ONE Alerts: New Articles Vincent Gache et al. 2010

During these studies, the scientists noticed that sister kinetochores - the protein structures that mark the site where a chromosome pair is split during cell division - are farther apart in metaphase II eggs from older mice at 16 to 19 months of age compared to eggs from young mice of 6 to 14 weeks of age, a finding that drew their attention to explore reduced cohesion as a primary source for age-related aneuploidy.

Gaea Times (by Simple Thoughts) Breaking News and incisive views 24/7 2010

According to the published evidence, the above proteins or their previously characterized orthologs from other species localized to interphase and/or spindle microtubules, kinetochores, midbody and the centrosome.

PLoS ONE Alerts: New Articles Vincent Gache et al. 2010

We propose that such networks may further evolve to describe not only MeMP, but also the mitotic spindle of metazoan organisms with its much more complex apparatus, including kinetochores, centrosomes and chromosomes.

PLoS ONE Alerts: New Articles Vincent Gache et al. 2010