from The American Heritage® Dictionary of the English Language, 5th Edition.
- noun Any of various structurally related polypeptides, such as bradykinin, that act locally to induce vasodilation and contraction of smooth muscle.
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun biochemistry Any of various
structurallyrelated polypeptidesof the autacoidfamily, such as bradykininand kallikrein, that act locally to induce vasodilationand contraction of smooth muscle.
from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
- noun any of a class of plant hormones that promote cell division and delay the senescence of leaves
from The American Heritage® Dictionary of the English Language, 4th Edition
He enjoyed the kinin 'a mite too much for my comfort.
"Then that John, he murmured," That old bitch is kinin 'all the little mice in the attic.
The enhanced contractile responses were accompanied by increased mRNA and protein expression for both kinin receptors, suggesting the involvement of transcriptional mechanisms.
These results provide evidence at the transcriptional level in a clinical model of tissue injury that up-regulation of kinin receptors are involved in the development of the early phase of inflammation and inflammatory pain.
The present study was designed to examine if nicotine could induce airway hyperresponsiveness through kinin receptors, and if so, explore the underlying mechanisms involved.
However, little is known about the regulatory effects of kinin receptors on the onset of acute inflammation and inflammatory pain in humans.
Kinins play an important role in regulation of pain and hyperalgesia after tissue injury and inflammation by activating two types of G-protein-coupled receptors, the kinin B1 and B2 receptors.
They reported that in endothelial cells, kinin B1 receptors activate iNOS via ERK-mediated phosphorylation of its Ser
The present study investigated the changes in gene expression of kinin receptors and the levels of their endogenous ligands at an early time point following tissue injury and their relation to clinical pain, as well as the effect of COX-inhibition on their expression levels.
It is in the autonomic system, is related to the signals coming into the dorsal horn, but has an additional pathway that can trigger local prostaglandin (at least) release independent of inflammatory substances separate from local kinin-kallikrein.