kraven

I think its most likely lizard takes to the sewers and kraven comes to town to hunt him, while black cat comes between spidey and mj. someguy

Sam Raimi Knows Nothing About Spider-Man 4; But Talks About It Anyway | /Film 2008

As for the film personally i rather go lizard and kraven then vulture. clarencesomerset

Rumor: Villain Confusion Stalls Spider-Man 4? Or is the Production Just on Winter Break? | /Film 2009

As for kraven he is a simple villain and could be a nice foil for spidey while he is trying to stop the lizard and help connors return to human form.

Spider-Man 4 To Feature New York City Centric Villain | /Film 2009

And it will hopefully not suck. mchops the lizard and kraven. c'mon we don't need anyone else. superozy

Spider-Man 4 To Feature New York City Centric Villain | /Film 2009

So then kraven goes after spidey who is a bigger prize. mchops he's either the lizard or carnage. the more likely scenario is lizard which i would prefer. redhawk23

Dylan Baker Back For Spider-Man 4 as Curt Connors… and also The Lizard? | /Film 2009

As for villains i personally want to see for sm4 is lizard and kraven.

New Female Lead Confirmed For Spider-Man 4, Romola Garai Auditioned… But Is It Black Cat? | /Film 2009

They would need Doc Oc alive, sandman back, vulture, mysterio, shocker, and Kraven the hunter in order to pull the original six off, but I could still see them substituting the hobgoblin for kraven.

John Malkovich to Play the Villain Vulture in Spider-Man 4? « FirstShowing.net 2009

But spidey is trying to stop kraven cause he learns lizard is conners and try to help him.

Dylan Baker Back For Spider-Man 4 as Curt Connors… and also The Lizard? | /Film 2009

I said it before personally i want lizard and kraven as spider-man 4 villains.

New Source Confirms Black Cat For Spider-Man 4, More Story Details Revealed? | /Film 2009

I think this would be good and if its lizard, kraven would be a good combo villain.

Dylan Baker Back For Spider-Man 4 as Curt Connors… and also The Lizard? | /Film 2009