Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. A metabolite, 2-amino-4-(2-aminophenyl)- 4-oxo-butanoic acid, that is an intermediate in the conversion of tryptophan to niacin.

Etymologies

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Examples

  • It might be pointed out here that kynurenine has since been recognized to occupy a central position in tryptophan metabolism in many organisms aside from insects, including mammals and fungi.

    Edward Tatum - Nobel Lecture

  • [5] Specific activity (U/mg) 0.0026 (organism grown on the standard medium with kynurenine [11]) [11] 0.0032

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  • C.; Warren, W.D.; Rover, S.; Mal - herbe, P.: Cloning and functional expression of human kynurenine 3 - monooxygenase.

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  • Cozzi, L.; Isacchi, A.: Functional characterization and mechanism of action of recom - binant human kynurenine 3-hydroxylase.

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  • R.; Molinari, A.; Ca - labresi, M.; Varasi, M.: Kynurenic acid-enhancing and anti-ischemic effects of the potent kynurenine 3-hydroxylase inhibitor FCE28833 in rodents.

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  • H.H.; Staudinger, H.: The regulatory function of l-kynurenine 3 - hydroxylase (EC 1.14.1.2) for the biosynthesis of pyridine nucleotides in anaerobically and aerobically grown Saccharomyces cerevisiae.

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  • Carpenedo, R.: Modulation of the kynurenine pathway in search for new neruoprotective agents.

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  • Shibata, Y.: Isolation of l-kynurenine 3-hydroxy - lase from the mitochondrial outer membrane of rat liver.

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  • Purification of l-kynurenine 3-hy - droxylase by affinity chromatography.

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  • Nisimoto, Y.; Takeuchi, F.; Shibata, Y.: Molecular properties of l-kynurenine 3-hydroxylase from rat liver mitochondria.

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