from Wiktionary, Creative Commons Attribution/Share-Alike License
- n. Any of a class of cyclic amides, that are the nitrogen analogs of lactones, formed by heating amino acids; the tautomeric enol forms are known as lactims.
from the GNU version of the Collaborative International Dictionary of English
- n. One of a series of anhydrides of an amido type, analogous to the lactones, as oxindol; a cyclic amide.
from The Century Dictionary and Cyclopedia
- n. The name of a class of organic compounds containing the group or They are formed by the elimination of water from γ-or δ-amino acids respectively, the reaction being characteristic of these two classes of compounds. They are simple cyclicacid amides.
Sorry, no etymologies found.
Lactacystin is a cyclic amide, which is also known as a lactam.
Why should you know which beta-lactam would appropriately treat a pneumonia patient with pseudomonal risk when the EMR prompts the appropriate selection for you?
Without a cell wall the organism is resistant to the effects of penicillin and other beta-lactam antibiotics, which disrupt bacterial cell walls.
In Europe, although ID physicians agree that about 40% of CAP is due to the atypicals,that beta-lactam antibiotics alone should be used anyway even though they have no activity against the atypicals.
Its lead product, Orapem, is an orally administered, becta-lactam antibiotic.
That change in that gene alters the resultant polymer chain just a little bit - but enough that the B-lactam mechanism no longer works.
We know that in environments heavy in B-lactam antibiotics, especially British hospitals specializing in open wound treatment, a new variant of Staphylococcus, not observed before, started to be noticed.
* A well understood environmental change B-lactam pollution.
The molecule in question had the beta lactam structure.
It was a bittersweet moment for one of the Medical Research Council's researchers: John Cornforth had boldly stated that if the beta lactam structure was correct he would give up chemistry and grow mushrooms instead.