Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. Plural form of lactam.

Etymologies

Sorry, no etymologies found.

Examples

  • In fact, the recruitment of similar resistance determinants within a single P. aeruginosa strain can determine a resistance phenotype to virtually all the available antipseudomonal beta-lactams, an occurrence that can be particularly dramatic when, as in the present case, resistance to beta-lactams is associated with resistance against aminoglycosides and fluoroquinolones. link (emphasis mine)

    Behe's Test

  • PFGE, the molecular-fingerprint technique, had not been invented yet,14 but the MRSA strains in the addicts and in the Henry Ford patients were resistant to exactly the same medications: methicillin and all the beta- lactams, and two additional classes of drugs.

    SUPERBUG

  • The strain must have been in pigs for a while, because in addition to methicillin and the rest of the beta–lactams, it was also resistant to tetracycline.

    SUPERBUG

  • In Pseudomonas aeruginosa, secondary beta-lactamases with extended substrate specificity can be responsible for acquired resistance to the most powerful antipseudomonal beta-lactams, such as expanded-spectrum cephalosporins and carbapenems.

    Behe's Test

  • Even with related substrates, some showed big changes others little, so without a good panel of beta-lactams to check the function of the crippled enzyme, the functional space represented is under sampled.

    Axe (2004) and the evolution of enzyme function - The Panda's Thumb

  • Antibiotics such as penicillin are called, collectively, beta-lactams, and enzymes that break down these antibiotics and confer drug resistance are called beta-lactamases, which is why the term beta-lactamase may pop up in this blog entry from time to time.

    Axe (2004) and the evolution of enzyme function - The Panda's Thumb

  • Blanchard, a professor at Albert Einstein's department of biochemistry, and his team have specifically targeted an enzyme called beta-lactamase, which can break down and disable beta-lactams, a large family of antibiotics that includes penicillin and its relatives.

    EurekAlert! - Breaking News

  • "When the M. tuberculosis genome was sequenced a few years ago, the presence of this beta-lactamase enzyme was discovered," Blanchard says, "which was surprising since beta-lactams have never been systematically used to treat TB."

    EurekAlert! - Breaking News

  • Greater sales of test kits with higher average selling prices, and ongoing growth in sales of Neogen's new BetaStar Combo test, that detects both beta-lactams and tetracycline were the primary reasons for this growth.

    Biotech Sector and Stocks Analysis from Seeking Alpha

  • Shigeta M, Komatsuzawa H, Sugai M, Suginaka H, et al. (1999) Effect of the growth rate of Pseudomonas aeruginosa biofilms on the susceptibility to antimicrobial agents: beta-lactams and fluoroquinolones.

    PLoS ONE Alerts: New Articles

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