from Wiktionary, Creative Commons Attribution/Share-Alike License
- n. Any of a family of macrolide tetraenes, isolated from Streptomyces, that is an antitumor antibiotic
Sorry, no etymologies found.
Individually, lankacidin and lankamycin, two antibiotics produced naturally by the microbe streptomyces, are marginally effective in warding off pathogens.
Mankin's group demonstrated that lankacidin prevents the ribosome from assembling new proteins.
Through the use of X-ray crystallography, which determines the arrangement of atoms in biological molecules, the Israeli team, led by Ada Yonath, a 2009 Nobel Prize winner, discovered the exact binding site of lankacidin in the ribosome.
Individually, lankacidin and lankamycin, two antibiotics produced naturally by the microbe streptomyces, are marginally effective in warding off pathogens, says Alexander Mankin, professor and associate director of the UIC Center for Pharmaceutical Biotechnology and lead investigator of the portion of the study conducted at UIC.
Having patients take the two antibiotics lankacidin and lankamycin at the same time is a more effective way to combat pathogenic bacteria than using either antibiotic on its own, a new study says.
Biochemical analysis and molecular modeling showed that lankamycin binds in the ribosomal tunnel right next to lankacidin.