from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. A triterpenoid sterol found in lanolin


Sorry, no etymologies found.


  • This lanosterol is then transformed in a complicated series of reactions into cholesterol, which has twenty-seven carbon atoms.

    Nobel Prize in Physiology or Medicine 1964 - Presentation Speech

  • The related substance lanosterol is perhaps less familiar but very important from the scientific point of view.

    Nobel Prize in Chemistry 1965 - Presentation Speech

  • They've documented the interactions of nearly every molecule, the way hydroxymethylglutaryl-coenzyme A reductase catalyzes the production of mevalonate, which gets phosphorylated and condensed before undergoing a sequence of electron shifts until it becomes lanosterol and then, after another 19 chemical reactions, finally morphs into cholesterol.

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  • Yoshida, Y.: The 4b-methyl group of substrate does not affect the activity of lanosterol

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  • L.E.; Saldou, N.; Jarnagin, K.; Swinney, D.C.: Cloning and functional expression of the cDNA encoding rat lanosterol 14a-demethylase.

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  • [11] Specific activity (U/mg) 0.0000084 (brain microsomes, substrate: lanosterol [6]) [6] Additional information

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  • P-45014DM catalyzes all three oxyge - nation steps from lanosterol to dimethylcholestatrienol [8];

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  • Yoshida, Y.: Occurrence of a P450 showing high homology to yeast lanosterol 14-demethylase

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  • Aoyama, Y.; Yoshida, Y.; Sonoda, Y.; Sato, Y.: Role of the 8-double bond of lanosterol in the enzyme-substrate interaction of cytochrome P-45014DM (lanosterol 14a-demethylase).

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  • Yoshida, Y.: Different substrate specificities of lanosterol 14a - demethylase (P-45014DM) of Saccharomyces cerevisiae and rat liver for 24 - methylene-24,25-dihydrolanosterol and

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