Definitions
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- noun organic chemistry A
triterpenoid sterol found inlanolin
Etymologies
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Examples
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This lanosterol is then transformed in a complicated series of reactions into cholesterol, which has twenty-seven carbon atoms.
Nobel Prize in Physiology or Medicine 1964 - Presentation Speech 1972
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The related substance lanosterol is perhaps less familiar but very important from the scientific point of view.
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They've documented the interactions of nearly every molecule, the way hydroxymethylglutaryl-coenzyme A reductase catalyzes the production of mevalonate, which gets phosphorylated and condensed before undergoing a sequence of electron shifts until it becomes lanosterol and then, after another 19 chemical reactions, finally morphs into cholesterol.
Wired Top Stories jmckeel 2012
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Aoyama, Y.; Yoshida, Y.; Sonoda, Y.; Sato, Y.: Role of the 8-double bond of lanosterol in the enzyme-substrate interaction of cytochrome P-45014DM (lanosterol 14a-demethylase).
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Yoshida, Y.: Occurrence of a P450 showing high homology to yeast lanosterol 14-demethylase
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Yoshida, Y.: The 4b-methyl group of substrate does not affect the activity of lanosterol
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L.E.; Saldou, N.; Jarnagin, K.; Swinney, D.C.: Cloning and functional expression of the cDNA encoding rat lanosterol 14a-demethylase.
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Yoshida, Y.: Different substrate specificities of lanosterol 14a - demethylase (P-45014DM) of Saccharomyces cerevisiae and rat liver for 24 - methylene-24,25-dihydrolanosterol and
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[11] Specific activity (U/mg) 0.0000084 (brain microsomes, substrate: lanosterol [6]) [6] Additional information
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P-45014DM catalyzes all three oxyge - nation steps from lanosterol to dimethylcholestatrienol [8];
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