from The American Heritage® Dictionary of the English Language, 4th Edition
- n. An abnormally low number of white blood cells in the circulating blood.
from Wiktionary, Creative Commons Attribution/Share-Alike License
- n. an abnormally low count of leukocytes, or white blood cells, in the blood
from The Century Dictionary and Cyclopedia
- n. Same as leucopenia.
from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
- n. an abnormal lowering of the white blood cell count
Sorry, no etymologies found.
An abnormally low count known as leukopenia might indicate bone-marrow failure, a disorder of the liver or spleen, lupus or exposure to radiation.
Recent studies have begun to unravel the cause of this phenomenon, and new research suggests that African Americans with the disease have a unique survival advantage if they have both a low white blood cell count (known as leukopenia) and a genetic variation that is found mainly in persons of African ancestry.
Side effects included pancreatitis and shingles that resulted in discontinuation of 5-acetylsalicylic acid, leukopenia corrected by withholding 6-mercaptopurine and self-resolved hepatitis.
Other findings include disseminated intravascular coagulation, bone marrow aplasia with leukopenia and thrombocytopenia, elevated liver enzyme values, hypocalcemia, hyponatremia and rhabdomyolysis.
To determine whether there is a relationship between the development of elevated aminotransferases, leukopenia or pancreatitis and the TPMT level in patients with IBD.
A competitive pathway also converts 6-MP to its cytotoxic 6-thioguanine nucleotides (6-TGNs) that are associated with bone marrow suppression (leukopenia, neutropenia, thrombocytopenia).
Common medical side effects include infection and leukopenia (8-15%), hepatitis (5-10%) and pancreatitis (3%).
They all present a risk of leukopenia, which can be fatal.
It has also been used to stimulate the production of granulocytes in patients receiving medication e.g., antineoplastic agents that may resuit in significant leukopenia.
The most common grade 3/4 adverse events in the iniparib treatment arm were neutropenia, anemia, thrombocytopenia, leukopenia and fatigue/asthenia.