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- n. A drug that down-regulates the secretion of gonadotropins
Sorry, no etymologies found.
It uses surgery or gonadotrophin-releasing hormone (GnRH) analogues such as leuprorelin to block the production of male producing sex hormones (androgens) that stimulate prostate cancer cells to grow.
Women in the Gn-RHa group received injected leuprorelin acetate depot, 3.75 mg intracutaneously, 6 times every 4 weeks.
The study randomized 174 patients with a laparoscopic diagnosis of endometriosis into four treatment arms: elagolix 150 mg once daily, elagolix 250 mg once daily, leuprorelin monthly depot (Prostap SR®), or placebo; in a double-blind, double-dummy design.
After completion of the initial three months of treatment, placebo and leuprorelin depot recipients were re-randomized in a double-blind manner to one of the elagolix arms for an additional three months.