Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun A third-generation
nonsedative antihistamine .
Etymologies
from Wiktionary, Creative Commons Attribution/Share-Alike License
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Examples
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Rx Pharmaceuticals: The company reported Rx Pharmaceuticals revenue of $97.5 million in second quarter of fiscal 2011, up 72% over the prior year driven by increased sales volume and higher sales of new products like Imiquimod cream generic version of Aldara and levocetirizine tablets, a generic version of Xyzal, for allergies.
unknown title 2011
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Rx Pharmaceuticals: The company reported Rx Pharmaceuticals revenue of $97.5 million in second quarter of fiscal 2011, up 72% over the prior year driven by increased sales volume and higher sales of new products like Imiquimod cream generic version of Aldara and levocetirizine tablets, a generic version of Xyzal, for allergies.
unknown title 2011
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The use of Xyzal® is contraindicated in: patients with a known hypersensitivity to levocetirizine or any of the ingredients of Xyzal®or to cetirizine (observed reactions range from urticaria to anaphylaxis); patients with end-stage renal disease with a creatinine clearance less than 10 mL/min or patients undergoing hemodialysis; and pediatric patients aged
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Xyzal® (levocetirizine dihydrochloride) in the U.S.
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Xyzal® (levocetirizine dihydrochloride) is indicated for the relief of symptoms associated with perennial allergic rhinitis and the treatment of uncomplicated skin manifestations of chronic idiopathic urticaria in adults and children 6 months of age and older, and for relief of symptoms of seasonal allergic rhinitis in adults and children 2 years of age and older.
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Xyzal® (levocetirizine dihydrochloride) is indicated for the relief of symptoms associated with perennial allergic rhinitis and the treatment of uncomplicated skin manifestations of chronic idiopathic urticaria in adults and children 6 months of age and older, and for relief of symptoms of seasonal allergic rhinitis in adults and children 2 years of age and older.
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"Physicochemical, pharmacological and pharmacokinetic properties of the zwitterionic antihistamines cetirizine and levocetirizine."
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Antihistamine Pharmacology Levocetirizine vs Cetirizine - Studies show significant improvement in subjective rating of symptoms following a course of Levocetirizine or Cetirizine compared to placebo - One 12 week program demonstrated statistically significant superiority in relieving symptoms using cetirizine in 6-12 year old population* "The comparison of cetirizine, levocetirizine and placebo for the treatment of childhood perennial allergic rhinitis" Pediatr Allergy Immunol.
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Antihistamine Pharmacology Levocetirizine: Beyond H1 Antagonism - Reduces expression of IL-6, IL-8, and GM-CSF - Reduces percentage representation of cell phenotypes known to contribute to inflammatory tissue damage (eosinophils, CD4+CD29+, CD4+CD212+, and CD4+CD54+) and expands percentages of CD4+CD25+ - Inhibits production of rhinovirus-induced ICAM-1 and NF-kappaB expression "Influence of cetirizine and levocetirizine on two cytokines secretion in human airway epithelial cells."
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April 2008, Vol. 9, No. 5, Pages 859-867 "Peripheral and central H1 histamine receptor occupancy by levocetirizine, a non-sedating antihistamine; a time course study in the guinea pig."
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