from The American Heritage® Dictionary of the English Language, 4th Edition
- n. See L-dopa.
from Wiktionary, Creative Commons Attribution/Share-Alike License
- n. A naturally-occurring amino acid found in food, converted into dopamine in the brain and body, and administered clinically in the management of Parkinson's disease and dopa-responsive dystonia.
from the GNU version of the Collaborative International Dictionary of English
- adj. A substance used as a therapy for parkinson's disease; the L form of Dopa; L-dihydroxyphenylalanine; L-hydroxytyrosine (C9H11NO4); also called L-dopa. In the body it is converted by the enzyme dopa-decarboxylase into dopamine, the form in which it is active in the brain, affecting neural impulse transmission.
from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
- n. the levorotatory form of dopa (trade names Bendopa and Brocadopa and Larodopa); as a drug it is used to treat Parkinson's disease
Sorry, no etymologies found.
The disease can be treated by replacing dopamine with a drug called levodopa, or L-dopa, but the drug loses its effectiveness over time.
It's now used to control symptoms between scheduled doses of levodopa, which is made by generic-drug makers including Apotex Inc.
"The drug levodopa, which is converted to dopamine, the chemical lost in Parkinson's disease, is our gold-standard treatment for relieving stiffness, tremors and rigidity," said Dr. Goetz.
While medications such as levodopa are highly effective for years, many patients continue to lose mobility despite higher doses.
Research using donated brain tissue has already led to major medical breakthroughs in the treatment and understanding of Parkinson's, including the development of anti-Parkinson's drugs, such as levodopa, which has revolutionised the way symptoms of the condition are controlled.
Treatments for symptom relief: Drugs levodopa with carbidopa, anticholinergics, surgery and deep-brain stimulation
“It is too early to say whether this could replace levodopa treatment or the current deep brain stimulation.”
Certain medications, particularly those containing levodopa (a substance that acts as a building block of dopamine), have known side effects.
Last year the London Times reported that the pope takes levodopa, a standard treatment, and before public appearances or officiating at a mass he reportedly also receives a shot of the fast-acting drug apomorphine hydrochloride, which is effective for only a short time.
But in the treatment of Parkinson's, we have gone from levodopa to levodopa.