from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. Plural form of ligase.


Sorry, no etymologies found.


  • APG had made good progress with a new process of sequencing that used a technique for gluing strands of DNA together rather than synthesizing new strands, using enzymes called ligases, that bond the fragments together.

    The $1,000 Genome

  • Kotorashvilli A, Russo S, Mulugeta S, Guttentag S, Beers M. Anterograde transport of surfactant protein C proprotein to distal processing compartments requires PPDY mediated association with Nedd4-2 ubiquitin ligases.

    Recent Neonatal Research Publications

  • Speaking of undersampling, it would have been good to look at the breakdown of common substrates of DD-peptidyl ligases and beta lactamases, such as m-[[phenylacetyl-glycyl]oxy]benzoic acid and see what the muations did to these activities.

    Axe (2004) and the evolution of enzyme function - The Panda's Thumb

  • Of course a ligase is also a type of enzyme, so for Berlinski to make a claim about ligases while excluding enzymes is nonsensical.

    Good Math, Bad Math, and David Berlinkski - The Panda's Thumb

  • Proteins of the PIAS family can act as SUMO-3 ligases, significantly enhancing the level of the substrate sumoylation

    PLoS ONE Alerts: New Articles

  • In outline, sumoylation involves the reversible covalent attachment of a SUMO protein moiety (about 11 kDa) to lysine residues in proteins through a three-step process, engaging the E1-activating molecules SAE1/SAE2, the E2-conjugating enzyme UBC9, and E3 ligases such as PIAS in mammalian cells that confer specificity

    PLoS ONE Alerts: New Articles

  • HECT ubiquitin ligases (HECT E3s) are key components of the eukaryotic ubiquitin-proteasome system and are involved in the genesis of several human diseases.

    BioMed Central - Latest articles

  • Animal HECT ubiquitin ligases: evolution and functional implications

    BioMed Central - Latest articles

  • The complex evolutionary history of HECT ubiquitin ligases in animals has been deciphered.

    BioMed Central - Latest articles

  • Restriction enzymes and ligases therefore allow the specific cutting and reassembling of portions of DNA. - Articles related to German government rejects aid for GM's Opel


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