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Nor have they the fine American hand for devising new verbs; to maffick, to limehouse, to strafe and to wangle are their best specimens in twenty years, and all have an almost pathetic flatness.
Run down the canal to limehouse and then past canary wharf.
The title refers to-and the work is set in-a limehouse where an obsessive scientist and his captive wife confront their emotionally crippled existence.