Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun A particular farnesyl-OH-transferase inhibitor.

Etymologies

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Examples

  • Today, clinical trials are underway using a failed cancer drug named lonafarnib that promises to block some of the progeria mutation's effect.

    Push to spur more drugs for deadly rare diseases 2011

  • Today, clinical trials are underway using a failed cancer drug named lonafarnib that promises to block some of the progeria mutation's effect.

    Push to spur more drugs for deadly rare diseases 2011

  • Today, clinical trials are underway using a failed cancer drug named lonafarnib that promises to block some of the progeria mutation's effect.

    USATODAY.com News 2011

  • David E, Sun SY, Waller EK, Chen J, Khuri FR, et al. (2005) The combination of the farnesyl transferase inhibitor lonafarnib and the proteasome inhibitor bortezomib induces synergistic apoptosis in human myeloma cells that is associated with down-regulation of p-AKT.

    PLoS ONE Alerts: New Articles 2009

  • Ph. D., at the Dana-Farber Cancer Institute in Boston launched a clinical trial of the FTI drug lonafarnib in 28 progeria patients, ranging in age from 3 to 15, from 16 countries.

    BioSpace.com Featured News and Stories 2008

  • Ph. D., at the Dana-Farber Cancer Institute in Boston launched a clinical trial of another FTI drug, lonafarnib, in 28 progeria patients, ranging in age from 3 to 15, from 16 countries.

    Phoenix Arizona Real Estate Local News and Business Directory 2008

  • The addition of lonafarnib to therapy with imatinib mesylate appears to be well tolerated and modestly synergistic in many patients with chronic myeloid leukemia who have failed treatment with imatinib alone.

    xml's Blinklist.com 2008

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