lysophosphatidic love



from Wiktionary, Creative Commons Attribution/Share-Alike License

  • adj. Describing a phosphatidic acid in which one or both acyl derivatives have been removed by hydrolysis.


Sorry, no etymologies found.


  • The findings may lead to a way to treat hydrocephalus using medication that prevents this fat molecule, called lysophosphatidic acid LPA, from binding to cells.

    Yahoo! News: Business - Opinion

  • Using a single strain of human mammary epithelial cells, we found that a wide variety of agonists, such as lysophosphatidic acid (LPA), uridine triphosphate, growth hormone, vascular endothelial growth factor, insulin-like growth factor-1 (IGF-1), and tumor, require EGFR activity to induce ERK phosphorylation.

    Journal of Biological Chemistry current issue

  • As a monoclonal antibody, Lpathomab functions like a 'molecular sponge' that binds to and neutralizes the bioactive lipid signaling molecule, lysophosphatidic acid LPA, thus silencing LPA receptors associated with the transmission of pain through the nervous system.

  • Autotaxin (ATX) is an extracellular lysophospholipase D that generates lysophosphatidic acid (LPA) from lysophosphatidylcholine (LPC).

    BioMed Central - Latest articles

  • There is also a tumor-marker test that measures levels of plasma lysophosphatidic acid (LPA) being developed.

    Gas Drilling

  • Lafleur J, Mwaikambo BR, Zhu T, Gagnon C, et al. (2009) The role of lysophosphatidic acid receptor (LPA1) in the oxygen-induced retinal ganglion cell degeneration.

    PLoS ONE Alerts: New Articles

  • Jeon ES, Moon HJ, Lee MJ, Song HY, Kim YM, et al. (2008) Cancer-derived lysophosphatidic acid stimulates differentiation of human mesenchymal stem cells to myofibroblast-like cells.

    PLoS ONE Alerts: New Articles

  • Lpathomab is a monoclonal antibody that binds to the bioactive lipid lysophosphatidic acid

    Health News from Medical News Today

  • MBOAT2 also prefers oleoyl-CoA, using lysophosphatidic acid and lysophosphatidylethanolamine as acyl acceptors.

    Journal of Biological Chemistry current issue

  • * AZX100 also significantly decreased expression of CTGF and collagen caused by endothelin and lysophosphatidic acid



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