Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- adjective organic chemistry Describing a
phosphatidic acid in which one or bothacyl derivatives have been removed byhydrolysis .
Etymologies
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Examples
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The findings may lead to a way to treat hydrocephalus using medication that prevents this fat molecule, called lysophosphatidic acid LPA, from binding to cells.
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Using a single strain of human mammary epithelial cells, we found that a wide variety of agonists, such as lysophosphatidic acid (LPA), uridine triphosphate, growth hormone, vascular endothelial growth factor, insulin-like growth factor-1 (IGF-1), and tumor, require EGFR activity to induce ERK phosphorylation.
Journal of Biological Chemistry current issue K. D. Rodland 2008
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As a monoclonal antibody, Lpathomab functions like a 'molecular sponge' that binds to and neutralizes the bioactive lipid signaling molecule, lysophosphatidic acid LPA, thus silencing LPA receptors associated with the transmission of pain through the nervous system.
unknown title 2011
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Autotaxin (ATX) is an extracellular lysophospholipase D that generates lysophosphatidic acid (LPA) from lysophosphatidylcholine (LPC).
BioMed Central - Latest articles Jian-Min Wu 2010
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There is also a tumor-marker test that measures levels of plasma lysophosphatidic acid (LPA) being developed.
Gas Drilling 2010
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Lafleur J, Mwaikambo BR, Zhu T, Gagnon C, et al. (2009) The role of lysophosphatidic acid receptor (LPA1) in the oxygen-induced retinal ganglion cell degeneration.
PLoS ONE Alerts: New Articles Hongyu Ying et al. 2010
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Lafleur J, Mwaikambo BR, Zhu T, Gagnon C, et al. (2009) The role of lysophosphatidic acid receptor (LPA1) in the oxygen-induced retinal ganglion cell degeneration.
PLoS ONE Alerts: New Articles Hongyu Ying et al. 2010
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Jeon ES, Moon HJ, Lee MJ, Song HY, Kim YM, et al. (2008) Cancer-derived lysophosphatidic acid stimulates differentiation of human mesenchymal stem cells to myofibroblast-like cells.
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Lpathomab is a monoclonal antibody that binds to the bioactive lipid lysophosphatidic acid
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MBOAT2 also prefers oleoyl-CoA, using lysophosphatidic acid and lysophosphatidylethanolamine as acyl acceptors.
Journal of Biological Chemistry current issue M. A. Gijon 2008
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