Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun genetics, oncology A
gene expressed inmelanocytes and involved in nevomelanocytic development; down-regulated in cases ofmelanoma
Etymologies
from Wiktionary, Creative Commons Attribution/Share-Alike License
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Examples
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Australian researchers tested icilin, a potent cooling agent in peppermint, on a sensory pathway called transient receptor potential ion channel melastatin subtype 8 TRPM8, found in the colon and other parts of the body.
Finding the Pathways to a Cause of Tinnitus Ann Lukits 2011
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Du J, Rowan S, Hershey CL, Widlund HR, et al. (2004) Transcriptional regulation of the melanoma prognostic marker melastatin (TRPM1) by MITF in melanocytes and melanoma.
PLoS ONE Alerts: New Articles Mitchell S. Stark et al. 2010
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Ion channel transient receptor potential membrane melastatin 6 and 7 (TRPM6 and TRPM7) play a central role in magnesium homeostasis, which is critical for maintaining glucose and insulin metabolism.
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It is an ion channel that is triggered by cold temperatures and small-molecule agonists and belongs to the melastatin subfamily - one of seven subfamilies of TRP proteins.
unknown title 2009
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