microplanar

Dilmanian FA, Zhong Z, Bacarian T, Benveniste H, Romanelli P, et al. (2006) Interlaced x-ray microplanar beams: a radiosurgery approach with clinical potential.

PLoS ONE Alerts: New Articles Raphaël Serduc et al. 2010

Laissue JA, Geiser G, Spanne PO, Dilmanian FA, Gebbers JO, et al. (1998) Neuropathology of ablation of rat gliosarcomas and contiguous brain tissues using a microplanar beam of synchrotron-wiggler-generated X rays.

PLoS ONE Alerts: New Articles Raphaël Serduc et al. 2010

Based on this well described normal tissue sparing effect of microplanar beams, we developed a new irradiation geometry which allows the delivery of a high uniform dose deposition at a given brain target whereas surrounding normal tissues are irradiated by well tolerated parallel microbeams only.

PLoS ONE Alerts: New Articles Raphaël Serduc et al. 2010

Normal rat brains were exposed to 4 focally interlaced arrays of 10 microplanar beams (52 µm wide, spaced 200 µm on-center, 50 to 350 keV in energy range), targeted from 4 different ports, with a peak entrance dose of 200Gy each, to deliver an homogenous dose to a target volume of 7 mm

PLoS ONE Alerts: New Articles Raphaël Serduc et al. 2010

It was based on the use of 2 arrays of 25 µm-wide microplanar beams (200 µm on-center distance) which generated an interlaced region where the distance between 2 MBs was 100 µm.

PLoS ONE Alerts: New Articles Raphaël Serduc et al. 2010

Dilmanian FA, Qu Y, Feinendegen LE, Pena LA, Bacarian T, et al. (2007) Tissue-sparing effect of x-ray microplanar beams particularly in the CNS: is a bystander effect involved?

PLoS ONE Alerts: New Articles Raphaël Serduc et al. 2010

Normal rat brains were exposed to 4 focally interlaced arrays of 10 microplanar beams (52 µm wide, spaced 200 µm on-center, 50 to 350 keV in energy range), targeted from 4 different ports, with a peak entrance dose of 200Gy each, to deliver an homogenous dose to a target volume of 7 mm

PLoS ONE Alerts: New Articles Raphaël Serduc et al. 2010

In the present study, no damage was visualized by MRI in 4 control rats irradiated by intersecting, non-interlacing arrays which created 700Gy microplanar peak doses spaced by 200 µm on-center (valley dose of 12.5 Gy at 1 cm depth).

PLoS ONE Alerts: New Articles Raphaël Serduc et al. 2010