Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • verb Simple past tense and past participle of misfold.
  • adjective of a protein or nucleic acid folded into an incorrect tertiary structure

Etymologies

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Examples

  • Understanding this process will give us new insights into a whole host of diseases, such as Alzheimer's, in which plaques in the brain are believed to be the result of misfolded proteins.

    Dr. Jeffrey H. Toney: Harvesting MMORPG Time Dr. Jeffrey H. Toney 2011

  • Understanding this process will give us new insights into a whole host of diseases, such as Alzheimer's, in which plaques in the brain are believed to be the result of misfolded proteins.

    Dr. Jeffrey H. Toney: Harvesting MMORPG Time Dr. Jeffrey H. Toney 2011

  • Piece 4: Cells have an internal quality-control mechanism that both detects and refolds misfolded proteins.

    Connecting the Pieces of the Alzheimer's Puzzle Matt Ridley 2011

  • Understanding this process will give us new insights into a whole host of diseases, such as Alzheimer's, in which plaques in the brain are believed to be the result of misfolded proteins.

    Dr. Jeffrey H. Toney: Harvesting MMORPG Time Dr. Jeffrey H. Toney 2011

  • What makes misfolded proteins appear in elderly brains?

    Connecting the Pieces of the Alzheimer's Puzzle Matt Ridley 2011

  • Research published last month by scientists at Brown University revealed that both parts of this mechanism—the detector and the refolder—are working, but overwhelmed, in diseased brains; they can't keep up with the workload of too many misfolded A-beta proteins.

    Connecting the Pieces of the Alzheimer's Puzzle Matt Ridley 2011

  • At the University of Chicago, Raymond Roos , a neurology professor and director of the ALS Clinic, is also studying how to clear misfolded proteins from the body.

    Deciphering Lou Gehrig's Disease Shirley S. Wang 2011

  • A protein with the wrong components, or that is misfolded, won't work as it is supposed to.

    Deciphering Lou Gehrig's Disease Shirley S. Wang 2011

  • Other researchers in the field say the finding is exciting, but further experiments are needed to show whether the misfolded ubiquilin 2 actually leads to a buildup of other toxic chemicals.

    Deciphering Lou Gehrig's Disease Shirley S. Wang 2011

  • Understanding this process will give us new insights into a whole host of diseases, such as Alzheimer's, in which plaques in the brain are believed to be the result of misfolded proteins.

    Dr. Jeffrey H. Toney: Harvesting MMORPG Time Dr. Jeffrey H. Toney 2011

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