Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun A particular antibiotic drug.

from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.

  • noun an antineoplastic drug (trade name Mithracin) used to treat cancer of the testes

Etymologies

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Examples

  • It has been reported earlier that thiazolidinediones (TZDs), could not repress the expression of resistin gene in the presence of mithramycin A (Sp1 binding inhibitor) in 3T3-L1 adipocytes

    PLoS ONE Alerts: New Articles Anil K. Singh et al. 2010

  • Next, we isolated RNA from cells pre-incubated with U1026, mithramycin, or vehicle controls and treated with M-CSF.

    PLoS ONE Alerts: New Articles Jennifer M. Curry et al. 2008

  • M-CSF-induced VEGF production from human monocytes is blocked by ERK inhibition and mithramycin.

    PLoS ONE Alerts: New Articles Jennifer M. Curry et al. 2008

  • To verify whether the inhibitory effect of mithramycin was due to inhibition of Sp1 binding, we attempted to use siRNA against Sp1.

    PLoS ONE Alerts: New Articles Jennifer M. Curry et al. 2008

  • (NS) or stimulated with rhM-CSF (100 ng / ml) (M-CSF), (M-CSF+MeOH), (M-CSF plus 8 nM, 40 nM, or 200 nM mithramycin) for 48 hours.

    PLoS ONE Alerts: New Articles Jennifer M. Curry et al. 2008

  • C) Freshly isolated human monocytes were cultured overnight in 5\% FBS and subsequently starved for 2 hours followed by pre-treatment with either methanol (vehicle control) or mithramycin (200 nM) in minimal media.

    PLoS ONE Alerts: New Articles Jennifer M. Curry et al. 2008

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