Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun biology The removal of damaged
mitochondria from acell prior tocell death
Etymologies
from Wiktionary, Creative Commons Attribution/Share-Alike License
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Examples
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The wild-type protein promotes the removal of impaired mitochondria by a specialized version of the autophagy pathway called mitophagy, delivering mitochondria to the lysosomes for degradation.
PhysOrg.com - latest science and technology news stories 2010
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The wild-type protein promotes the removal of impaired mitochondria by a specialized version of the autophagy pathway called mitophagy, delivering mitochondria to the lysosomes for degradation.
PhysOrg.com - latest science and technology news stories 2010
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Transport to the perinuclear region was also blocked by a mutation in Parkin, indicating that this stage of mitophagy is also regulated by the protein.
PhysOrg.com - latest science and technology news stories 2010
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Cherra SJ 3rd, Kulich SM, Tandon A, Park D, et al. (2009) Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission.
PLoS ONE Alerts: New Articles Angela C. Poole et al. 2010
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Transport to the perinuclear region was also blocked by a mutation in Parkin, indicating that this stage of mitophagy is also regulated by the protein.
PhysOrg.com - latest science and technology news stories 2010
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Parkinson's disease, but how Parkin stimulates mitophagy and whether the pathway goes wrong during pathogenesis is unknown.
PhysOrg.com - latest science and technology news stories 2010
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Granted, in order to export an aggregate out of the cell, it would have to cross a membrane, but this would be no more difficult topologically than mitophagy.
Research Blogging - All Topics - English Ouroboros: Research in the biology of a ouroboros 2010
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Geisler S, Holmstrom KM, Skujat D, Fiesel FC, Rothfuss OC, et al. (2010) PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1.
PLoS ONE Alerts: New Articles Angela C. Poole et al. 2010
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Granted, in order to export an aggregate out of the cell, it would have to cross a membrane, but this would be no more difficult topologically than mitophagy.
Research Blogging - All Topics - English Ouroboros: Research in the biology of a ouroboros 2010
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Vives-Bauza C, Zhou C, Huang Y, Cui M, de Vries RL, et al. (2009) PINK1-dependent recruitment of Parkin to mitochondria in mitophagy.
PLoS ONE Alerts: New Articles Angela C. Poole et al. 2010
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