Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun Plural form of
morphant .
Etymologies
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Examples
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Moreover, mtmr8 morphants show loss of arterial endothelial cell identity in dorsal aorta, which is effectively rescued by low concentration of PI3K inhibitor, and by over-expression of dnPKA mRNA or vegf mRNA.
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The morphants show a reduction in total abundance of pax6a, but its pattern of expression is same as that of wild-type embryos (E) The morphants show an increased level of pax2 expression compared to wild-type embryos.
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The morphants have a smaller head and eyes, severe edema of the heart
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(C) Expression of s hh in morphants and wild-type embryos at 24 hpf.
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The morphants show massive apoptosis (blue dots indicate the TUNEL-positive cells) concentrated primarily in the head region compared to a few scattered positive cells in control and wild-type embryos.
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(A) Lateral views of morphants (rpl11 MO, upper panel), controls (control MO, middle panel), and wild-type embryos (WT, lower panel) at 24 hpf.
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The morphants show a proper hindbrain patterning compared to the wild-type embryos.
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Semi-quantitative RT-PCR of p53, p53 target genes (p21, mdm2) and apoptotic markers (bax and puma) transcript levels relative to actin in the morphants and wild-type embryos at 4, 8, 12, and 48 hpf.
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Severe morphological deformities with almost a complete absence of brain subdivisions (black arc) were observed in the morphants.
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We also observed other phenotypes commonly associated with RP morphants [17], such as hypoplasia of the yolk sac extension, abnormalities in the ear, and delayed pigmentation of the eyes.
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