Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. Any substance used to modify gene expression

Etymologies

Sorry, no etymologies found.

Examples

  • Finally, the control morpholino, which is a five base mismatch of the original MO, did not result in any phenotype, apoptosis or upregulation of the p53 pathway (

    PLoS ONE Alerts: New Articles

  • AVI's proprietary, intrinsically charge-neutral, phosphorodiamidate morpholino oligomer PMO

    AVI BioPharma and Leading Researchers at Karolinska Institutet Form Collaboration to Identify RNA-Based Therapeutic Candidates for Treatment of Extensively Drug-Resistant Tuberculosis (XDR-TB) - Yahoo! Finance

  • AVI-7100 employs the Company's patented PMOplusā„¢ technology that selectively introduces positive charges to a phosphorodiamidate morpholino oligomer PMO backbone to improve selective interaction between the drug and its target.

  • AVI BioPharma is focused on the discovery and development of RNA-based drugs utilizing proprietary derivatives of its antisense chemistry (morpholino-modified phosphorodiamidate oligomers or PMOs) that can be applied to a wide range of diseases and genetic disorders through several distinct mechanisms of action.

    Marketwire - Breaking News Releases

  • RNA and morpholino antisense oligonucleotides were microinjected into the yolk of one-cell stage embryos.

    PLoS ONE Alerts: New Articles

  • Upon the introduction of an antisense morpholino (2 mM) against granzyme G to knock-down endogenous gene function, all embryos were arrested at the 2 - to 4-cell stages of egg cleavage, and the de novo synthesis of zygotic RNAs was decreased.

    BioMed Central - Latest articles

  • Using a PDGFR tyrosine kinase inhibitor, a morpholino oligonucleotide specific to

    Elites TV

  • AVI BioPharma is focused on the discovery and development of RNA-based therapeutics utilizing proprietary derivatives of its antisense chemistry (morpholino-modified phosphorodiamidate oligomers or PMOs) that can be applied to a wide range of diseases and genetic disorders through several distinct mechanisms of action.

    BioSpace.com Featured News and Stories

  • AVI BioPharma is focused on the discovery and development of RNA-based medicines utilizing proprietary derivatives of its antisense chemistry (morpholino-modified phosphorodiamidate oligomers or PMOs) that can be applied to a wide range of diseases and genetic disorders through several distinct mechanisms of action.

    Marketwire - Breaking News Releases

  • Working with a class of compounds known as antisense phosphorodiamidate morpholino oligomers, or PMOs, scientists first performed a series of studies with mouse and guinea pig models of Ebola to screen various chemical variations.

    PhysOrg.com - latest science and technology news stories

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