Definitions
from The American Heritage® Dictionary of the English Language, 4th Edition
- n. Any of a group of vertebrate oncogenes whose product, a DNA binding protein, is thought to promote the growth of tumor cells.
Etymologies
Examples
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For example, in cancer that had spread from the pancreas to the lung, Campbell found that a gene called myc had been mutated.
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Furthermore, leukemic malignancies were forced through integration of fusion-genes that mimic chromosomal alterations, such as myc-IgH
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This man who got this country into so myc debt and other troubles wants the AMericans to give credit to ANYTHING he has to say?
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It is possible now to produce a stem cell from almost any other human cell instead of using embryos as needed previously, albeit the risk of tumorigenesis due to c-myc and retroviral gene transfer remains to be determined.
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Even so, as in myc constituency it's simplay Labour or Conservative, I'll vote Conservative.
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To test the roles of other oncogenes and environmental stimuli, Leder created a second OncoMouse, in which two activated proto-oncogenes, ras and myc, were engineered into the chromosome and expressed in breast cells.
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Many of the genes and pathways that enabled each of these six behaviors had concretely been identified—ras, myc, Rb, to name just a few.
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The mouse embodied the maturity of cancer genetics: scientists had created real, living tumors not just abstract, etiolated foci in petri dishes by artificially manipulating two genes, ras and myc, in an animal.
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Rapid cellular proliferation, or the insensitivity to growth-arresting signals, or tumor angiogenesis, can all largely be explained by aberrantly activated and inactivated pathways such as ras, Rb, or myc in cancer cells.
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If myc was permanently activated in the embryo, the embryo turned into a ball of overproliferating cells, then involuted and died through unknown mechanisms.
Comments
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